7,759 research outputs found

    Overweight and Obesity Knowledge Assessment of Alaskan Nurse Practitioners

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    The purpose of this project was to describe Alaskan Nurse Practitioners (NPs) current practice and beliefs regarding overweight and obesity, and to identify barriers that may prevent evidence based management. A descriptive study was conducted using a convenience sample of 116 Alaskan NPs who completed The Treatment of Obesity Questionnaire. Findings revealed which factors NPs considered to determine risk status; their current management strategies; barriers to treatment; and, their beliefs regarding the etiology of obesity. An open-ended question revealed other treatment strategies, barriers, and beliefs regarding the treatment of overweight and obese patients

    Don't judge a book by its cover. factitious disorder imposed on children-report on 2 cases

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    Factitious Disorder Imposed on Another (FDIA), also known as Munchausen Syndrome by Proxy (MSbP) is a very serious form of child abuse. The perpetrator, usually the mother, invents symptoms or causes real ones in order to make her child appear sick. Usually this is due to a maladaptive disorder or to an excessive of attention-seeking on her part. We report here two new cases of FDIA. The first one is a 9-year-old boy with a history of convulsive episodes, reduced verbal production, mild psychomotor disorder and urological problems who underwent several invasive procedures and hospitalizations before a diagnosis of FDIA was made. The second is a 12 year-old girl with headache, abdominal pain, lipothymic episodes, seizures and a gait impairment, who was hospitalized in several hospitals before an FDIA was diagnosed

    Hadronic interactions of primary cosmic rays with the FLUKA code

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    The measured fluxes of secondary particles produced by the interactions of cosmic rays with the astronomical environment represent a powerful tool to infer some properties of primary cosmic rays. In this work we investigate the production of secondary particles in inelastic hadronic interactions between several cosmic rays species of projectiles and different target nuclei of the interstellar medium. The yields of secondary particles have been calculated with the FLUKA simulation package, that provides with very good accuracy the energy distributions of secondary products in a large energy range. An application to the propagation and production of secondaries in the Galaxy is presented.Comment: 8 pages, 4 figures; Contribution to the 34th International Cosmic Ray Conference, July 30 to August 6, The Hague, Netherlands; fixing a typo in the y-axis label of Fig.

    Related RNAs in lepidopteran cells after in vitro infection with Hyposoter didymator virus define a new polydnavirus gene family

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    In the present study, we describe the isolation and the characterization of three different Hyposoter didymator virus (HdV) lepidopteran host-expressed genes, the products of which might interfere with the host physiology during parasitism. In this report, we study the expression of HdV genes in Sf9 cells infected with HdV since results indicate that the Sf9 model mimics to some extent the in vivo model and may be utilized to study expression of HdV genes in lepidopteran host cells. This system allowed us to isolate three HdV-specific cDNAs, termed M24, M27, and M40. cDNA nucleotide sequence analysis demonstrated significant regions of homology. The three cDNAs displayed repeated sequences arranged in tandem array that might have evolved through domain duplication. Similar to other previously described polydnavirus host-expressed genes, two intron positions have been found in the M24 leader region. The cDNAs corresponded to RNAs of 1.6, 1.6, and 2.3 kb that are also detected in parasitized Spodoptera littoralis larvae. They are encoded by different genes likely located on different HdV DNA molecules. Corresponding RNAs are detected early postinfection and remain detectable for at least 10 days postinfection. They encode secreted glycine- and proline-rich proteins. An antiserum raised against a baculovirus recombinant M24-encoded protein detected similar proteins in the culture medium of infected lepidopteran cells and in parasitized host hemolymph. We propose that the three cloned genes belong to an HdV gene family specifically expressed in parasitized lepidopteran hosts, (C) 1999 Academic Press

    A generalized notion of consistency with applications to formal argumentation

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    We propose a generic notion of consistency in an abstract labelling setting, based on two relations: one of intolerance between the labelled elements and one of incompatibility between the labels assigned to them, thus allowing a spectrum of consistency requirements depending on the actual choice of these relations. As a first application to formal argumentation, we show that traditional Dung's semantics can be put in correspondence with different consistency requirements in this context. We consider then the issue of consistency preservation when a labelling is obtained as a synthesis of a set of labellings, as is the case for the traditional notion of argument justification. In this context we provide a general characterization of consistency-preserving synthesis functions and analyze the case of argument justification in this respect

    Effect of magnesium therapy on nocturnal leg cramps: a systematic review of randomized controlled trials with meta-analysis using simulations

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    Background and objective. Nocturnal leg cramps (NLC) are common in primary care and may cause severe pain and sleep disturbance. We systematically reviewed the effectiveness of magnesium in treating NLC and the side-effect profile of magnesium compared to placebo. Methods. We searched Medline, Embase, Cochrane Library, ClinicalTrials.gov, the International Standard Randomised Controlled Trial Number and the International Clinical Trials Registry Platform registries until August 2012. All randomized controlled trials (RCTs) comparing magnesium therapy for NLC in adults with any other comparator were eligible. Two investigators independently selected, extracted data from and rated the risk of bias of relevant studies. To compensate for the heterogeneity in outcome measures, simulations were used to summarize the data. Results. Seven RCTs were included in the review (n = 361), all comparing magnesium to placebo. Three of these trials included only pregnant women. The difference in the median number of leg cramps per week between the placebo and the intervention groups was 0.345 (quantile 2.5%: −0.133, quantile 97.5%: 0.875). This difference was 0.807 (quantile 2.5%: 0.015, quantile 97.5%: 1.207) in the three studies involving only pregnant women and 0.362 (quantile 2.5%: −0.386, quantile 97.5%: 1.148) in the others. Overall gastrointestinal side effects were slightly more common with magnesium therapy than with placebo. The strength of this evidence was weak, mainly due to small study sizes and short follow-up. Conclusions. Magnesium therapy does not appear to be effective in the treatment of NLC in the general population, but may have a small effect in pregnant women. Further research using better designed RCTs is necessar

    Re-examining the X-Ray versus Spin-Down Luminosity Correlation of Rotation Powered Pulsars

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    The empirical relation between the X-ray luminosity (in the 2-10 keV band) and the rate of spin-down energy loss of a sample of 37 pulsars is re-examined considering recent data from ASCA, RXTE, BeppoSAX, Chandra, and XMM-Newton. The data show a significant scatter around an average correlation computed including statistical and systematic errors. All the X-ray luminosities are found to lie below a critical line corresponding to a maximum efficiency of conversion of rotational energy into X-rays varying between 0.1 and 80%. The large dispersion of the X-ray luminosity below the critical line indicates that other physical parameters uncorrelated with the period and period derivative need to be included to account for the observed emission at X-ray energies. We indicate a few possibilities that all conspire to lower the luminosity

    Fluka Estimations concerning Obstacles in the LHC Magnets.

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    The effect of the impact of the full energy LHC proton beam with an object left in the beam pipe is investigated in order to assess the conditions for a superconducting magnet's quench. FLUKA simulations indicate that a quench would happen about 20 m downstream from the impact for a current through the object being several orders of magnitude lower than the nominal beam current. If such a strict current limit (decreasing with increasing obstacle's thickness) is not exceeded in operational conditions, the obstacle might be destroyed without causing any quench, being the vaporization time dependent on its shape and movement. However, any rise of the traversing current above the mentioned limit would result in a beam dump and the obstacle remaining in the machine
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